Alda Marques
Ana M. Sousa; Ana C. Sousa
PRISMA - Pulmonary Rehabilitation: a response for patients with COPD in an InduStrialized environment and its implication on lung MicrobiotA
PRISMA capitalizes on MicroRESPIRA, which found high abundance of bacteria, allergic and pathogenic agents for the human respiratory tract above the admissible values set by the National Legislation in the homes of patients with chronic obstructive pulmonary disease. Therefore, these people are at higher risk of having acute exacerbations, which causes severe individual, social and economic impacts. However, little has been done to improve patients’ awareness about the impact their home environment might have in their disease and quality of life. Pulmonary rehabilitation (PR) is an evidence-based intervention known to improve patients’ education, reduce symptoms, exacerbations, hospital admissions and quality of life however, it is highly inaccessible. PRISMA will overcome this barrier. It will also enhance our understanding of the mechanisms behind the effectiveness of PR by exploring the modulation of lung microbiota, since acute exacerbations might be caused by individual’s microbiota, however, this is still poorly understood.
Projet OHMs
OHM(s) concerné(s)
  • OHM Estarreja
Biologie, Éco-épidémiologie, Médecine, Santé publique


Alda Marques is currently a senior lecturer at School of Health Sciences (ESSUA) and a research member of the Institute for Biomedicine (iBiMED), University of Aveiro, Portugal. Since 2009, coordinates the LAB3R-Respiratory Research and Rehabilitation Laboratory at ESSUA. Marques is currently an active member of the European Respiratory Society, American Association of Respiratory Care, International Lung Sound Association, Portuguese Society of Pneumology and is the President of the cardiorespiratory group of the Portuguese Physiotherapy Association. Her research interests are by working with multidisciplinary teams, to: i) explore the effectiveness and different models of delivery PR; ii) improve patients with respiratory diseases and their families management and iii) develop and implement new measures or core outcome sets to be used clinically.
Marques has more than 100 publications in peer-reviewed journals, 3 published books and 8 book chapters in respiratory diseases. She has been principal investigator of 12 funded research projects (FCT/FCG/COMPETE2020) related with respiratory disease or dementia management, 3 of them ongoing. She has been also a member of the research team of 5 other funded research projects, one an international multicenter trial. Marques has vast experience in supervising Post-docs, PhDs and Master students. The results from these studies have and will continue to contribute to a further development of the non-pharmacological management of patients with chronic diseases and their families. Marques has received 18 awards for her work, one of which the first prize for the best work conducted in “Rehabilitation & Chronic Care”, awarded by the European Respiratory Society.


Célia Freitas (PhD) is an Adjunct Professor at the School of Health Sciences at the University of Aveiro and a collaborator researcher at the Center for Health Technology and Services Research (CINTESIS) at the University of Porto. She completed her PhD in Didactics and Education in 2012 at the department of Education and Psychology (University of Aveiro).
During her career as a nurse (up to 2013), she has been dedicated to the health promotion and developed several projects in the community, namely, the continuous care at home integrated in the National Network of Continuous Care (RNCCI), whose main mission is to provide health care and social support to dependents. She also focuses her work on health literacy and chronic disease management, like respiratory, diabetes, cancer and she consider this a challenge to improve the quality of life and health outcomes in people with chronic diseases, and develop of self-management behaviors.
Since 2012 she has published one paper in...